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doi:10.3390/ijms23021005

1 Introduction In the context of T regulatory lymphocytes, innate Treg (nTreg, or natural Treg, which leaves the thymus in the form of mature cells) and acquired Treg (iTreg, induced Treg, generated by naive CD4+ T response to antigenic stimulation) have been characterized ( 1) Modulation of APC (Antigen-presenting cell)