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show similar up-regulation of PanIN lesion formation, inflammation, fibrosis and stellate cells activation in the same animal model, but with a shorter exposure to cigarette smoke (6 weeks) (38)

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The 1980s also represent a specific cultural moment in American tobacco advertising a last flourish of full-scale branded merchandise before the regulatory environment shifted which gives promotional pieces from that era a particular historical specificity that collectors increasingly recognize and value

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