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Persistent mitochondrial damage in airway epithelium of COPD patients is further evidenced by the increased expression of PINK1, a sensor for damaged mitochondria, and PPARGC1, a regulator of mitochondrial biogenesis [20, 46]

Some people say that it is not only the nicotine but also the smoke of the cigarette that is the root cause of all the trouble

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"There's no other single thing that a person can do to improve their health more than quitting smoking," said Julia Thorington, NP, who works with Franciscan Healthy Living Center Crawfordsville