Cortisone has been abused by some people, leading to a bad name for this drug in some peoples minds
Latino-Martel P, Arwidson P, Ancellin R, Druesne-Pecollo N, Hercberg S, Le Quellec-Nathan M, et al
Beyond Pleasure: Aversion Pathways While the mesolimbic dopamine system mediates nicotines rewarding effects, nicotine also activates the medial habenulainterpeduncular nucleus (MHbIPN) circuit, which produces aversive sensations such as nausea at high doses
Baskaran, V., Murray, R
Smoking - Still A Major Driver Of Risk We have made progress but smoking is still a major global issue Cigarettes are the only legal consumer product that, when used as intended, will kill half of all long-term users. Dr Scott Gottlieb - FDA Commissioner Undoubtedly we have made significant progress when it comes to the health impacts of smoking, but we still have a long way to go, and that progress might even be reversing