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This gives us a clue that there might be a connection, but randomized controlled studies would be the best way to discover whether semaglutide can actually help people quit smoking. The side effects of semaglutide are well understood and include: abdominal pain constipation diarrhea nausea and vomiting These could deter some people from using this drug to quit smoking

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Kulkarni et al

The CDC also says that those who smoke have double the chance of developing gum disease as non-smokers and that treatment for gum disease (like surgeries and medications) dont have quite the same effects as they do for non-smokers