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Target Dose (Monotherapy/Combination): The common target dose used in major clinical trials is 2.4 mg per week

Who can benefit the most from B12 injections

This theory is supported by the results of studies in which the formate level in the retinal tissue was five times lower after systemic administration of formate compared to that measured after systemic administration of methanol at the corresponding dose (Garner et al

Oxidative stress and the resultant hyperpermeability play a vital role in the pathogenesis of diabetic retinopathy

But if you HAVE high blood pressure, the reductions are stark and large, even on the lower dose