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The number of permutations, 250,000, was chosen to give a high degree of certainty for the permutation p-value, specifically, a 99% confidence interval for the p-values would have a precision (half width) of approximately 0.001

Second, they assume (but never actually state) that the impact of plain packaging on smoking by children (the principal target) and adults was supposedly going to be greater than anything we have previously observed in the entire history of tobacco control

When the indicator light is red, the protection mechanism is activated

The single jet torch provides a focused, wind-resistant flame for consistent performance