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Examples Repaglinide (Prandin) Dosage Initial: 0.52 mg before each meal, up to four times daily Maximum: 16 mg daily, 4 mg per dose Nateglinide (Starlix) Dosage Initial: 60120 mg before meals, up to three times daily Maximum: 360 mg daily, 120 mg per dose Possible side effects include: Hypoglycemia (lower risk than sulfonylureas) Weight gain Bile acid sequestrants Primary mechanism(s) of action Bile acid sequestrants were originally developed and approved to lower LDL-cholesterol

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Familial hypercholesterolaemia (FH) Familial hypercholesterolaemia (FH) is a group of inherited genetic defects leading to increased concentrations of low-density lipoprotein (LDL-C) and, secondarily, total cholesterol (TC), with elevated LDL-C being one of the main diagnostic criteria [155]

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[PubMed] [Google Scholar] 87.Misra U.K., Kalita J., Das A