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Neutrophil extracellular trap mitochondrial DNA and its autoantibody in systemic lupus erythematosus and a proof-of-concept trial of metformin

[4] The relatively rapid escalation used in the Phase 2 studies likely contributed to the high adverse-event rates and to the notable discontinuation seen in the obesity trial

Guergueltcheva V, Azmanov DN, Angelicheva D, Smith KR, Chamova T, Florez L, Bynevelt M, Nguyen T, Cherninkova S, Bojinova V, Kaprelyan A, Angelova L, Morar B, Chandler D, Kaneva R, Bahlo M, Tournev I, Kalaydjieva L

Table 3 Growth hormone receptor (GHR) conditional knockout (KO) mice

Dry temperature was set as 350