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Research has not shown any notable difference between nicotine derived from the tobacco leaf and synthetic nicotine as it pertains to the way the human body and brain react nor as it pertains to levels of addictiveness
Maeda, K
The Helpline is here for Oklahomans who are trying to quit using smokeless tobacco or those who want to support their loved ones through the quitting process. Smokeless tobacco is even more habit forming than cigarettes because it contains up to four times as much addictive nicotine than found in cigarettes
You might even need to use supplemental oxygen just to get through the day
Am J Physiology-Renal Physiol
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