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In the initial stage, the periodontal pocket depths are at most 4 mm and are defined by horizontal bone loss

In favor of this hypothesis, glycerol a main e-cigarette humectant, constituting 3070% of most e-liquids, has been shown to inhibit oral cancer cell growth and enhance cisplatin-induced apoptosis 27

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Finally, the cross-sectional nature of the study did not allow for disentangling the effects of smoking from other factors (e.g., personality traits) that would lead someone to become dependent on tobacco