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To advance this field, more refined and tissue-selective strategies are under investigation, including minimally invasive delivery systems and prodrugs engineered to become active exclusively within senescent microenvironments

Table 9: Results at Week 52 in a Trial Comparing TRESIBA to Insulin Glargine U-100 in Adult Patients with Type 2 Diabetes Mellitus on OAD(s)* *OAD: oral antidiabetic agent **The change from baseline to end of treatment visit in HbA1c was analyzed using ANOVA with treatment, region, sex, and anti-diabetic treatment at screening as fixed effects, and age and baseline HbA1c as covariates

Vomiting Some people may experience vomiting, especially when they first start taking semaglutide

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Risk of death and cardiovascular outcomes with thiazolidinediones: a study with the general practice research database and secondary care data