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The present study complies with the PRISMA guidelines 190 (Supplementary Tables 9 and 10 and Supplementary Information 1.5) and Guidelines for Accurate and Transparent Health Estimates Reporting (GATHER) recommendations 191 (Supplementary Table 11)

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4 Pathway changes associated with cellular damage and inflammation in brain A systematic review of the effects of active and passive smoking of conventional cigarettes, electronic cigarettes and tobacco heating products indicated that active and passive smoking induce oxidative stress and inflammatory responses in peripheral tissues (Kopa-Stojak and Pawliczak, 2024

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Research into the benefits and risks of CBD use still is in its infancy, and many of the purported perks are not yet fully backed by science