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Safety and toxicity are critical considerations when developing nanoparticle-based therapies for AD

This balancing act helps maintain vascular stability and prevents the system-wide collapse that can occur when nitric oxide levels are out of sync

10.1080/14787210.2019.1656064 158 MarsheV

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However, recent studies show that these supposedly inert anions can be recycled in vivo to form NO, representing an important alternative source of NO to the classical l-arginineNO-synthase pathway, in particular in hypoxic states