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Designing foods that support portion control Another key to successful reformulation for the GLP-1 era is in maximising nutrient density delivering more protein, fibre and essential nutrients in fewer calories per bite

Mechanisms investigated Metabolic-pathway research converges on a small set of enzymatic and receptor targets, and these compounds map onto different ones they are not interchangeable: NNMT inhibition (5-Amino-1MQ): studied as a small-molecule inhibitor of nicotinamide N-methyltransferase, an enzyme implicated in cellular NAD/SAM metabolism

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10.3390/biom12050714 29 FanJ.HanY.SunH.SunS.WangY.GuoR.et al (2023)