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These modifications include an Ala8Aib amino acid substitution and attachment of a C18 fatty diacid side chain at Lys26 via a linker that promotes albumin binding, significantly prolonging circulation time compared to native GLP-1

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Environ Int (2012) 40:3943

Additional peptides with neuropathy-relevant mechanisms Beyond the primary peptides discussed above, several additional compounds demonstrate mechanisms relevant to neuropathy through distinct biological pathways