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Quantifying time-varying sensitivity of macroinvertebrates to global change drivers To quantify the time-varying sensitivity of macroinvertebrates to each global change driver at each site, we used a locally weighted state-space regression method 30,34,35,36

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To counter these threats, cells have evolved molecular chaperones that mitigate the toxic effects of such proteins by preferentially binding to exposed hydrophobic regions, thereby facilitating their refolding or targeting them for degradation 62,94

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Data tables: National Drug Strategy Household Survey 2019 - 2