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First appearing in Europe in the mid-2000s, spice products have since developed into hundreds of different chemical variants
Ex-smokers in this group who had quit smoking five years or more prior to the study and had gone on to use e-cigarettes showed a higher risk of lung cancer (adjusted HR=1.65) and of lung-cancer-specific death (adjusted HR=4.46) than those who had not taken up using e-cigarettes
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