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The recent improvement in Vuse performance is encouraging, although the Vapour category continues to be impacted by illicit proliferation

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Studies on cannabis cigarettes or waterpipes were also excluded, along with those that did not meet our objectives (studies evaluating consumption patterns, epidemiology, flavor preferences in youth, among others)

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This decline in prevalence can translate into a reduction in all-cause mortality between the Base and Modified Case scenarios, with the prevention of ~476,000 premature deaths by the year 2,100 (Figure 6)