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In a cross-sectional clinical study, smokers had on average 15%20% higher insulin requirements and higher serum triglyceride concentrations compared with non-smokers, increasing to 30% in heavy smokers (Madsbad et al., 1980)

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Oxidative stress and free radicals in COPDimplications and relevance for treatment

Participants reporting 2 to 5 cigarettes per day had elevated hazards across outcomes, ranging from 1.26 for atrial fibrillation to 1.57 for heart failure, and showed higher cardiovascular disease mortality (hazard ratio 1.57) and all-cause mortality (hazard ratio 1.60) versus never-smokers