FIGURE 1 During AKI, dysfunctional mitochondria can induce the expression of peroxisome proliferator-activated receptor- coactivator 1 (PGC-1), which facilitates mitochondrial biogenesis and supports the maintenance of mitochondrial structure, function, and quantity
It plays a crucial role in neutralizing free radicals, supporting detoxification, and maintaining overall cellular health
Growth factor-loaded functionalized gold nanoparticles as a potential targeted treatment for acute renal failure
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Under pathological conditions, excessive H 2 O 2 /O/OH causes dysfunction of NSCs, which in turn participates in neurodegenerative diseases such as Alzheimer's [292]