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A "dee dar" (as Notts people call Yorkshiremen due to their accents!) trying to speak in a "Brummie" dialect would probably end up with a black eye for "taking the piss" (if talking to a Brummie) although no one would know what was said as he would have been virtually unintelligible to ANYONE

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[96] Essentially, smoking disturbs the enzyme activity (adenine nucleotide translocator and mitochondrial superoxide dismutase) in mitochondria that is essential for their proliferation, thus reducing their numbers

For example, a visible line indicates a negative result, while the absence of a line signifies a positive display for a particular drug

NOTE: This piece written by Health Blogger and Reflux Expert David Gray wipeoutreflux.com