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L i , the lung cancer rates by smoking group, can be estimated based on the following equations: These solve directly to give: or alternatively The variance of the logarithm of the rate estimate, L i , can then be estimated approximately as: The inverse of var log L i can be used as a weighting factor in meta-analysis

Overall, the existing literature remains preliminary and largely hypothesis-generating, with no longitudinal studies capable of establishing causality or dose-response relationships

its history, legends, literature, cultivation, social and hygienic influences, commercial development, industrial processes and governmental regulation

Coffee and chocolate: Bitter, dark coffee roasts balance well with sweet but strong cigars

The most famous such steam rings were those produced during the mid-20th century by Douglas Leigh's billboard on the Hotel Claridge in New York City's Times Square, advertising Camel cigarettes