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Tobacco smoking likely began as a specialized practice associated with ritual practices, but over time became more ubiquitous and widespread

Measures Socio-demographic variables and moderators Socio-demographic measures included age, education level, ethnicity, and smoking status, and were assessed using previously validated measures adapted from the International Cigarette Packaging Study surveys and the Brazil National International Tobacco Control (ITC) survey

Chronic inflammation induced by cigarette smoke exposure releases various inflammatory components, including the cytokines, TNF-, IL-1 and IL-6, and the chemokines, CXCL1 and CXCL8

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