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Previously, investigators have observed increase in IL-6 and TNF- 42 , and others have shown a decrease in TNF-, IL-6 and MCP1, but an increase in IL-8 43 following aerosolized e-liquid exposure in human alveolar macrophages as well as in THP-1 cells

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Prevention and cessation recommendations extend to all forms of nicotine in children and young adults including combustible cigarettes, e-cigarettes, hookahs and smokeless tobacco