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10.1038/ncb1999 Nat

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Some studies have found that intermittent hypoxia leads to the following changes: a decrease in total antioxidant capacity, an increase in MDA serum levels, a decrease in the activity of antioxidants (SOD, GSH-Px and GSR) of the testis and epididymis and a significantly reduced number of epididymal sperm [23, 24]

Following the enzyme-catalyzed glutathionylation of the substrate, the deglutathionylation occurs as decribed above