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Concluding Remarks The difference in the physical stability of co-formulations 17 and 18 became most apparent after 14 days

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demonstrated in a PD rat model that VNS increased NE in the LC and significantly inhibited the activation of microglia and astrocytes induced by 6-Hydroxydopamine (6-OHDA), exerting a protective effect on DA neurons in the SN (110)

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