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The numbers of mutations within any cancer cell will vary between individuals, but experts said this study shows the additional mutational load caused by tobacco

But has nicotine been given an unfairly bad rap

While acknowledging that further studies with shorter periods of preoperative smoking interventions were necessary, due to the difficulty of such a long period of abstinence for many smokers, this study made it very clear that the physicians and care team surrounding a smoking patient could have a significant and meaningful impact

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J Anal Toxicol 41:670678