Each time a cell divides, telomeres shorten, eventually triggering cellular senescence or apoptosis - effectively limiting the replicative lifespan of normal somatic cells to approximately 50-70 divisions (the Hayflick limit)
It has been shown to have antiaging properties and has been studied for its effect on telomerase activity, oxidative stress and immune modulation
Immunosuppressants work by lowering the activity of the immune system, and while there is no strong evidence that GLP-1 drugs interfere with these treatments, potential interactions should always be evaluated on a case-by-case basis
Patients complete a virtual intake, a licensed clinician evaluates eligibility, and an appropriate prescription follows, either an FDA-approved brand GLP-1 or a compounded semaglutide or tirzepatide from a licensed compounding pharmacy
doi: 10.1210/js.2019-00078 80 TamNNGaoYLeungYKHoSM