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Though testosterone can be beneficial in men with anemia, research indicates it can cause polycythemia in greater than 20 percent of men treated with testosterone replacement therapy

In individuals with pre-existing gastrointestinal conditions such as inflammatory bowel disease, coeliac disease, or irritable bowel syndrome, introducing any new supplement may temporarily affect bowel habits as the digestive system adapts

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With tirzepatide removed from the shortage list, 503B compounding of standard tirzepatide formulations has been significantly curtailed