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Circulating gut microbiota metabolite trimethylamine N-Oxide (TMAO) and changes in bone density in response to weight loss diets: the POUNDS Lost Trial

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Physiological melanin hyperpigmentation is the result of increased melanin biosynthesis by melanocytes in the basal cell layer of the oral epithelium, but pathological melanin pigmentation may be the result of increased number of normal melanocytes or atypical melanocytes, of increased melanogenic activity of normal or atypical melanocytes, or of both

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