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These findings suggest that IQOS uptake is occurring among current adult smokers, which is in alignment with both the principles of harm reduction and the United States Food and Drug Administrations (FDA) conclusion that IQOS has potential benefit to population health 20

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A detailed explanation, supported by any necessary data, of why use of the food component characterized by the claim is of importance in human nutrition by virtue of its presence or absence at the levels that such claim would describe