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Funding This work was supported by the Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme (2019), the National Natural Science Foundation of China (82103931 and 82003443), the Guangzhou Science and Technology Project (202002030255), and Young Elite Scientists Sponsorship Program by CAST (2019QNRC001)

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Figure 4 Figure 5 ENDS exposure induces lipid dysregulation and ferroptosis in mice We noticed that the level of cell death detected by TUNEL staining (either apoptosis or necrosis) does not fully match with lung tissue destruction by ENDS as shown in histological staining

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