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Once active, L-5-MTHF works alongside Vitamin B12 to convert homocysteine into methionine, which is then used to produce S-adenosylmethionine (SAMe), the body's universal methyl donor

Mitochondria and mood: mitochondrial dysfunction as a key player in the manifestation of depression

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According to Healthline , vitamin B12 injections are considered generally safe, but some do have allergic reactions or sensitivity

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