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More than a quarter of youth in middle and high school have tried e-cigarettes. These statistics are particularly troubling, since teen e-cigarette users are 4-7 times as likely to begin smoking traditional cigarettes (SOURCE)

The lower lip is softer and has more nerve endings, which can make a pouch there feel more irritating or spicy on your gums

Wang M, Zhou T, Song Q, Ma H, Hu Y, Heianza Y, et al

Long-Term Health Risks Chewing tobacco is widely associated with higher long-term health risks due to tobacco content

However, the safety of e-cigarettes is debated, and a growing body of evidence is suggesting several adverse health effects