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In a clinical trial in 8,179 participants with atherosclerotic cardiovascular disease, 70% of whom had a history of ischemic stroke or TIA, treatment with IPE 4 g/day in 2 divided doses plus statin vs statin therapy alone reduced fatal or nonfatal stroke by 28% (2.4% vs 3.3%

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The antibiotics given by IV include some of the same types given as pills, such as carbapenems, cephalosporins, fluoroquinolones, and penicillin