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doi: 10.1146/annurev.immunol.22.012703.104635 21 OGarraA.BrittonW

10.1016/s0092-8674(00)81369-0 67 MangoniA.GrassiM

The 25.4-fold increase in collagen IV synthesis observed with the GHK-Cu and hyaluronic acid combination represents a specific and quantifiable mechanism: collagen IV is the primary structural collagen of the basement membrane, the organized layer that underlies all epithelial and endothelial surfaces

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The main surgical options are: 1