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It is a tripeptide composed of glutamate, cysteine, and glycine, with a unique gamma peptide bond between the glutamate side chain and cysteine that protects it from normal peptidase degradation

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In a cellular immune response, antigen-presenting cells (APCs) in the skin release interleukin (IL)-12 and interleukin (IL-23), which activate type 1 (Th1), and type 17 (Th17) T cells