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An average reduction in body weight of approximately 15%

Long-term cardiovascular outcome data is not yet available for Retatrutide, and this will be an important focus of ongoing Phase 3 trials

The modification of ferroptosis and abnormal lipometabolism through overexpression and knockdown of potential prognostic biomarker perilipin2 in gastric carcinoma

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Retatrutide: The New Triple-Agonist Weight Loss Treatment Medically reviewed by Dr Clair Grainger Last reviewed: 30 Dec 2025 Retatrutide is the latest weight loss medication thats currently in phase 3 clinical trials