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After the stomach acid does its work, B12 binds with haptocorrin proteins that reside in the stomach

Patients with Lebers disease, a rare hereditary optic neuropathy, should avoid methylcobalamin supplementation as it may precipitate or worsen optic atrophy in affected individuals

This may improve absorption and minimize peptide degradation during digestion

Healthcare providers recommend inserting the needle at a 90-degree angle into the fatty layer beneath your skin, roughly to inch deep, which targets the subcutaneous space without hitting muscle