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With regard to tGSH levels (a) no significant change was observed in old versus young adults (Pardo-Andreu et al., 2006), but (b) a decrease with age was reported in old adult sub-groups (ages 6066, 7278, 8187 and 90 yrs) (Prez et al., 2020)

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A smaller barrel spreads a small dose across more length, making it easier to measure accurately