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HIFs are protective in the short-term, but chronic HIF stabilization in the RPE can exert detrimental effects [15,16,17,18], from which the metabolic shift is most relevant for the present study

PMID 16723674

(5) Disease or health-related condition means damage to an organ, part, structure, or system of the body such that it does not function properly (e.g., cardiovascular disease), or a state of health leading to such dysfunctioning (e.g., hypertension)

Includes Tamper

It is a standard size flame, but easily capable of filling the role of an everyday lighter as it can handle both thick and thin ring gauges with ease