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In transgenic mice expressing human Siglec-8, treatment with an anti-Siglec-8 monoclonal antibody significantly suppressed IgE-mediated MCs degranulation and effectively blocked MRGPRX2-mediated, non-IgE-dependent MCs activation and pruritus (95)
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High prevalence of bronchiectasis in emphysema-predominant COPD patients
49 A mild elevation in COHb may indicate an exposure source, and a more-severe poisoning may be prevented if it is identified early
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