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In such studies, the extent of lung inflammation can be assessed by BALF analysis (quantification of inflammatory cells, such as neutrophils and macrophages, and molecular markers, such as cytokines and chemokines), histopathology (assessment of lung infiltration by inflammatory cells, such as neutrophils and pigmented macrophages), and both lung gene and protein expression analysis [41]

As a result of these diseases, smoking may cause an additional 60,000 deaths per year, Dr

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