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[54] found that GSSG/2GSH levels and reduction potential in erythrocytes reflect genetic differences between individuals

The half-lives of unbound IGF-1, IGF-1 in a binary complex, and IGF-1 in a ternary complex are less than 10 minutes, 25 minutes, and more than 16 hours respectively meaning that IGF-1 activity is tightly regulated by its binding proteins

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2011, Hyslop PA, Hinshaw DB, Halsey WA, Schraufsttter IU, Sauerheber RD, Spragg RG, Jackson JH, Cochrane CG: Mechanisms of oxidant-mediated cell injury