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Several studies have shown that endothelial function assessed by biomarkers for endothelial function including circulating levels of nitrate/nitrite, NO, von Willebrand factor (vWF), cellular adhesion molecules, vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1), endothelial progenitor cells (EPCs) and endothelial microparticles (EMPs), endothelin-1 and activity of endothelial NOS (eNOS) other than physiological assessment for endothelial function was impaired in smokers

The post and graphic suggest that the combination of caffeine and aspartame can lead to the generation of excitotoxins

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Dimensions: 5472 x 3648 px | 46.3 x 30.9 cm | 18.2 x 12.2 inches | 300dpi Date taken: 24 January 2025 Photographer: IMAGO/Matrix Images / Stringer More information: This image could have imperfections as its either historical or reportage

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