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Data-driven archetype assignment Rather than assigning archetypes by hand-written rules, the five taxonomy dimensions were one-hot encoded (29 binary features) and clustered using k-means

Patients were randomized 1:1 to receive Toujeo (n=466) or Tresiba (n=463) subcutaneously between 6 PM and 8 PM over 24 weeks

Is topiramate (Topamax) approved for weight loss

ISCHAEMIC PRECONDITIONING A phenomenon whereby a brief interruption of blood supply to the brain protects the tissue from a subsequent ischaemic episode

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