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Activated phagocytic cells produce hypochlorous acid, the product of myeloperoxidase (MPO) activity that is stimulated during immune activation, resulting in the 3-CT derivative

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Although neutrophils are known to aggravate liver injury in a variety of diseases [115], an early study using antibodies against adhesion molecules to block neutrophil cytotoxicity did not protect suggesting that neutrophils do not aggravate APAP-induced liver injury [114]

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