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4.3 Clinical implications: balancing benefits and risks in practice Healthcare providers should implement targeted strategies to address nutraceutical-related risks, focusing on comprehensive reviews of nutraceutical-drug interactions and the discontinuation of non-essential supplements in high-risk populations, such as the elderly or those undergoing polypharmacy (102)

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Maintenance therapy usually involves injections every two to three months

Importantly, ongoing studies are now deepening the understanding of the effects of GLP-1RAs in different HF cohorts (e.g., patients with HFpEF and those with advanced HF) [144,145,146]