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Seek medical advice if you experience: New-onset insomnia or significant sleep disruption that persists after starting B12 supplementation Paradoxical fatigue : Worsening tiredness despite taking B12, which may indicate an underlying condition requiring investigation Neurological symptoms : Tingling, numbness, balance problems, or cognitive changes, which could suggest B12 deficiency or other neurological conditions Mood changes : Anxiety, agitation, or depression that develops or worsens after starting supplementation Palpitations or rapid heartbeat : Though rare, some individuals report cardiovascular symptoms that should be evaluated It's important to note that sleep disturbances may be unrelated to B12 supplementation

Lifestyle and Other Precautions Your daily habits also play a significant role in your recovery

doi: 10.3389/fnut.2022.853846 Received 13 January 2022 Accepted 14 February 2022 Published 04 April 2022 Volume 9 - 2022 Edited by Minhao Xie, Nanjing University of Finance and Economics, China Reviewed by Lanting Zeng, South China Botanical Garden (CAS), China

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